Research Keywords:
- allergy
- asthma
- atopic dermatitis
- mast cells
- eosinophils
- Inhibitory receptors
Research Highlights:
Prof. Levi-Schaffer's expertise is in the area of immunopharmacology of allergy focusing on mast cells and eosinophils, their activating and inhibitory receptors, their cross-talk ("The Allergic Effector Unit") for a better prophylaxis/treatment of allergic diseases. Moreover, her lab studies the role of mast cells and eosinophils in hypoxia (allergy, COPD), in mastocytosis, and in candidiasis; the crosstalk between atopic dermatitis and asthma with the microbiome; and the role of mast cells in psoriasis and psoriatic arthritis. Her lab is also developing novel monoclonal antibodies and bispecific antibodies against activating and inhibiting receptors on mast cells and eosinophils for the treatment of allergy and in non-allergic diseases with different pathogenesis and of selected solid tumors.